Others use it as a stand-alone supplement alongside intermittent fasting or low-carb routines
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49 In another phase 1 study conducted in 37 Japanese patients, the most common treatment-related side effects were nausea, vomiting, abdominal discomfort, diarrhea, and headache, mostly mild to moderate in severity
Additionally, the expression of tight junction-associated proteins in colonic tissues was significantly upregulated after the intervention, suggesting that the intervention may attenuate damage to intercellular tight junctions triggered by inflammatory factors, thereby protecting the intestinal mucosal barrier integrity
10.1186/s13048-025-01700-8 J Ovarian Res